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What is Glutamine? Benefits, Uses & Side Effects

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Glutamine is an essential amino acid that plays many functions in the human body. Also, it’s a building block of protein and an important part of the immune system. Our body can naturally produce this amino acid.

Out body needs 20 essential and non-essential amino acids which can work to create several proteins. Also, this essential amino acid founds in many food items. Here you will know that why this acid is important for your health. So, let’s get started:

What Is It?

Glutamine is an essential amino acid, and amino acid molecules play many roles in the human body. The primary purpose of this acid is to serve as the building block of protein. And proteins are vital for the organs of the body. They can also serve other functions like transporting substances in the blood and fighting against harmful viruses and bacteria.

Like other amino acids, it founds in two different forms as L-Glutamine and D-Glutamine. These two acids are identical, but they have some different molecular arrangements—a form of glutamine found in foods and supplements known as the L-Glutamine. Few supplements list it as L-glutamine, but others simply use the broader term glutamine.

This acid is commercially available in the form of powder and capsules. You can consume the glutamine by your mouth for sickle cell disease. It’s also good to improve nutrition and help people recover from surgery, injuries, burns, bone marrow transplant, HIV and AIDS complications, radiation, and cancer chemotherapy. Also, it is suitable for many other uses.

Moreover, glutamine is essential to maintain the balance of the body’s acid-base ratio. It is also used to remove excess ammonia. It’s a toxic waste product of deamination reactions. Glutamine enables to removes the harmful ammonia from kidneys and connect to the acids before it is excreted. Therefore, glutamine is also an essential molecule for the immune system and intestinal health.

Glutamine formula

What Does Glutamine Do?

It can support many functions such as support the immunity system, gastrointestinal integrity, insulin secretion, neurological activity, and muscle protein synthesis. Actually, this acid can supply 35% of nitrogen to the muscle to synthesize protein. In turn, this will promote protein synthesis. The benefit of glutamine that it can maintain a high nitrogen balance in the muscle.

Also, it can prevent muscle breakdown, however, you need to retain more muscle. A lean body shows that your body has less fat, so glutamine may help in the reduction of overall body fat. But there are no evidence and study available to prove these effects. Or, glutamine has not recommended as a fat burner.

But some references show that it can help to add or retain the lean muscle tissues, which means you will be leaner. At the point of minor fat burning, there are some studies that suggest the ability of glutamine supplements to manipulate tissue insulin sensitivity.

What Are The Benefits?

One of the main benefits of glutamine is its repairing ability. It can also reduce muscle soreness and improve muscle repair and glycogen repletion. Another advantage is that it can repair and restore the digestive tract. Some studies suggest that glutamine supplements can help to support the health and integrity of the intestinal lining.

When people have issues like IBS, Celiac disease, and other digestive problems, glutamine is involved in the prescription. Also, it can help to heal the intestinal lining and reduce the symptoms like bloating. With the bio-availability of glutamine considerably higher than the glutamine peptides. Other researches are conducted with the free L-glutamine form to support this form as the preferred use. Some more benefits of glutamine are:

  • Good for immune system health
  • Help to improve the intestinal health
  • Sufficient for muscle gain and exercise performance
  • Support good health
  • Use as a fitness supplement
  • Good for muscle protein
  • Can improve the gut syndrome
  • Improve gut inflammation
  • Support the intestine health
  • Reduce muscle damage
  • Intestinal health regulation

Glutamine formula

Uses of Glutamine

Glutamine is an FDA-approved prescription that is used for sickle and cell disease. Consuming it two times a day by mouth can prevent the sudden complications of sickle and cell disease. And, it might also avoid the number of times people are in the hospital and the hospital’s number of days for the crisis.

  • It seems to reduce the risk of some severe infections through a feeding tube and reduce the chances of death in people due to severe burns.
  • It also seems to reduce the risk of some infections in people because of severe burns. But it can not decrease the chances of death.
  • Many types of research show that glutamine keeps the bacteria from moving out of the intestine and infecting other body parts after significant injuries.
  • Glutamine also helps to reduce the risks of hospital-acquired infections in people who are ill. It does not seem to reduce the death chances in critically ill people.
  • People who are suffering from HIV-AIDS must have to take glutamine supplements. Taking it by mouth can help to absorb the food better and gain weight. A 40 grams dose of glutamine can help to produce the best effects.
  • It is also suitable for those who had surgery. The dose of glutamine with intravenous nutrition seems to prevent the days spent in the hospital after surgery, especially when people suffer from major abdominal surgery.
  • Moreover, it can help to reduce infections and improve the recovery after bone marrow transplant. Not all people who had bone marrow transplants get benefits from it.
  • Glutamine does not seem to prevent the death risks after any kind of surgery.

Side Effects

When the mouth takes glutamine, it’s likely safe for adults to get 40 grams of glutamine daily. Side effects of this amino acid are generally mild includes dizziness, heartburn, and stomach pain. Also, glutamine is likely safe for adults when it is taken with the IV in doses up to 600 mg of body weight daily.

There are no adverse effects of a high dosage of glutamine blood safety markers not specially examined. Some other studies have also reported some minimal safety concerns regarding short-term supplements of up to 14 grams daily.


Glutamine has naturally produced by the body and found in many foods. Estimatidely that a typical diet contains 3 to 6 grams in a whole day. It can provide furl for the immune system and intestinal cells. Also, it helps to keep the connections in the intestines healthy.

During severe injuries and surgeries, your body can not produce the optimal amount. Therefore, glutamine supplements better use with beneficial effects on the immune system and overall health.

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